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13 5 Testosteroni Testosteronin faasin I metabolia on laaja ja tärkeimmät testosteronin metaboliareitit ovat hiilen 17 hapettuminen, -renkaan kaksoissidoksen pelkistyminen sekä hiilen 3 pelkistyminen. 8 Suurin osa tunnetuista metaboliiteista muodostuu näitä reittejä tai näiden yhdistelmiä pitkin. Testosteronin, kuten muidenkin 17β-OH-steroidien eräs hyvin tunnettu metaboliareitti on entsymaattinen hapettuminen 17β-OH-steroididehydrogenaasin avulla. Reaktiossa muodostuvat 17-ketosteroidit, esimerkiksi androsteenidioni, ovat testosteronin päämetaboliitteja. ndrosteenidioni ja testosteronin muita ihmisellä esiintyviä metaboliitteja on esitetty kuvassa 2 (I-XII). androsteenidioni androsteroni epiandrosteroni 5α-androstaani- (I) (II) (III) 3α,17β-dioli (IV) 5α-dihydrotestosteroni 5β-dihydrotestosteroni 5α-androstaani- 5 β-androstaani- (V) (VI) 3α,17β-dioli (VII) 3α,17β-dioli (VIII) 5α-androstaani- 1,4-androstadieeni- 4,6-androstadieeni- 17b-hydroksi-4,6-3β,17β-dioli (IX) 3,17,dioni (X) 3,17,dioni (XI) androstadieeni-3-oni (XII) Kuva 2. Testosteronin metaboliitteja.

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The use of Stanozolol will suppress natural testosterone production in all men and should only be used in conjunction with exogenous testosterone. Failure to supplement with exogenous testosterone will put the man into a low testosterone state. The form of testosterone is inconsequential.

Once all Stanozolol use is ended and any and all anabolic steroids have cleared the body natural testosterone production will begin again. It will not occur overnight and it is recommended that a Post Cycle Therapy (PCT) plan follow use. A PCT plan will aid in recovery. A PCT plan will not complete recovery, this will still take several months, but it will speed up the process and increase the odds of a successful recovery.

Important Note: Women do not need to supplement with testosterone during Stanozolol use.

Important Note: Natural testosterone recovery assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) during use and that no prior low testosterone condition existed prior to use.

Steroidien vaikutus

steroidien vaikutus

The use of Stanozolol will suppress natural testosterone production in all men and should only be used in conjunction with exogenous testosterone. Failure to supplement with exogenous testosterone will put the man into a low testosterone state. The form of testosterone is inconsequential.

Once all Stanozolol use is ended and any and all anabolic steroids have cleared the body natural testosterone production will begin again. It will not occur overnight and it is recommended that a Post Cycle Therapy (PCT) plan follow use. A PCT plan will aid in recovery. A PCT plan will not complete recovery, this will still take several months, but it will speed up the process and increase the odds of a successful recovery.

Important Note: Women do not need to supplement with testosterone during Stanozolol use.

Important Note: Natural testosterone recovery assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) during use and that no prior low testosterone condition existed prior to use.

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