5mg a day was too much and he was having bad side effects, extreme lethargy, he stopped eating,and drinking and his diarrhea actually got worse. Half a pill ever other day was not enough his stool was normal the first day then back to diarrhea the second. Half a pill mg a day seems to be the formula that works for him. He tolerates it well,and his stool remains normal. Mischief is much more active and healthy now,and is actually gaining weight. I am very pleased. Like I said I think it saved his life. Also the drug is very inexpensive $10 bucks a month
Steroid-resistant nephrotic syndrome is an inherited condition that impairs ability of the kidneys to filter protein out of the urine. This disease is usually diagnosed shortly after birth, and always before 3 months of age. Affected infants have difficulty getting nutrients and swell with excess fluid. One of the important proteins lost in the urine of these patients is albumin. Albumin is a protein that acts like a sponge, drawing extra fluid from the body into the bloodstream where it remains until removed by the kidneys. When albumin leaks into the urine, the blood loses its capacity to absorb extra fluid from the body, causing edema. This disease leads to kidney failure that doesn’t respond to steroidal medications, and affected individuals usually require a kidney transplant before the age of 20. With careful medical care and a timely transplant, affected children can live well into adulthood.
The most common side effect of topical corticosteroid use is skin atrophy. All topical steroids can induce atrophy, but higher potency steroids, occlusion, thinner skin, and older patient age increase the risk. The face, the backs of the hands, and intertriginous areas are particularly susceptible. Resolution often occurs after discontinuing use of these agents, but it may take months. Concurrent use of topical tretinoin (Retin-A) % may reduce the incidence of atrophy from chronic steroid applications. 30 Other side effects from topical steroids include permanent dermal atrophy, telangiectasia, and striae.