Side effects of using topical corticosteroids

But not every side effect is a bad one. Some are downright welcome. Take finasteride . Introduced in 1992 to treat noncancerous enlargement of the prostate gland , it was found to regrow hair (and is marketed for that purpose under the name Propecia). Today, millions of men use a low dose of finasteride to treat male pattern baldness . Similarly, minoxidil , originally marketed as an oral tablet for high blood pressure , was found to grow hair in those using it. Today, as a topical lotion or foam, it is a popular over-the-counter remedy for baldness.

A subpopulation of patients with asthma may have aspirin-sensitive asthma which may include chronic rhinosinusitis complicated by nasal polyps ; severe, potentially fatal bronchospasm; and/or intolerance to aspirin and other NSAIDs. Because cross-reactivity between aspirin and other NSAIDs has been reported in such aspirin-sensitive patients, CELEBREX is contraindicated in patients with this form of aspirin sensitivity [see CONTRAINDICATIONS ]. When CELEBREX is used in patients with preexisting asthma (without known aspirin sensitivity), monitor patients for changes in the signs and symptoms of asthma.

And, exacerbating these two age-related erosive events, some catabolites of tryptophan can lead to the formation of mutagenic nitrosamines or the activation of an immunosuppressive receptor (which is usually triggered by toxicants such as xenobiotics), promoting carcinogenesis (Mezrich, et al., 2010; Chung & Gadupudi, 2011).

The consumption of a supplement of tryptophan will likely nurture or augment these disastrous age-associated disease states, by raising injurious tryptophan derivatives (particularly in the presence of a vitamin B6 deficiency, an insufficiency of stomach acid, a magnesium deficit, and a vitamin B3 deficiency).

Furthermore, tryptophan side effects in regards to greater mortality were shown in animal experiments (., Catrina, et al., 2001) using melatonin, whereas the study authors cautioned:

“[...] melatonin had a deleterious effect on the survival rate raising the question whether it is correct to assume that the hormone shows lack of adverse reactions.” [emphasis added]

In regard to serotonin's involvement in the promotion of higher mortality, one of its anti-longevity effects is conceivably the reabsorption of phosphate (a pro-inflammatory chemical) by the kidneys since klotho, an anti-aging protein, facilitates the excretion of phosphate from the kidneys (Peat, Nov. 2012).

Since tryptophan, serotonin, and melatonin meddle with basic energy production in cells, and since metabolic efficiency and functionality decreases proportionally with aging (Fannin, et al., 1999; O'Toole, et al., 2010) due to various factors, it seems coherent in biological terms that these substances are less prevalent, thus less “essential” or needed, in older people, as a further decrease of an already suboptimal general metabolic working order will aggravate physiological function systematically, increase the risk for disease (as exemplified and foreshadowed with tryptophan side effects), promote the aging process, and explains the increased mortality related to the administration of these substances.

Several tryptophan side effects, such as tryptophan's carcinogenic activities, the deterioration of metabolic energy function, and the promotion of hypertension, can rather readily account for a greater death rate.

If yes, you don't have to deliberately tweak your carb intake. When you start taking coconut oil, it will automatically help you "determine" how much carb you have to take to fulfill your daily requirement. All you need to do is just listen closely to your body needs. People tend to take in more calories than they need when they ignore the signals that their body gives. For example, when you see your favorite food, you would just go for it without "asking" your body whether it is hungry and does really need to take it now or not. This is when people start to gain weight.

Side effects of using topical corticosteroids

side effects of using topical corticosteroids

If yes, you don't have to deliberately tweak your carb intake. When you start taking coconut oil, it will automatically help you "determine" how much carb you have to take to fulfill your daily requirement. All you need to do is just listen closely to your body needs. People tend to take in more calories than they need when they ignore the signals that their body gives. For example, when you see your favorite food, you would just go for it without "asking" your body whether it is hungry and does really need to take it now or not. This is when people start to gain weight.

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