Due to its effects on gastric acid secretion, esomeprazole can reduce the absorption of drugs where gastric pH is an important determinant of their bioavailability. Like with other drugs that decrease the intragastric acidity, the absorption of drugs such as ketoconazole, atazanavir, iron salts, erlotinib, and mycophenolate mofetil (MMF) can decrease, while the absorption of drugs such as digoxin can increase during treatment with esomeprazole. Esomeprazole is an enantiomer of omeprazole. Concomitant treatment with omeprazole (20 mg daily) and digoxin in healthy subjects increased the bioavailability of digoxin by 10% (30% in two subjects). Co-administration of digoxin with NEXIUM is expected to increase the systemic exposure of digoxin. Therefore, patients may need to be monitored when digoxin is taken concomitantly with NEXIUM.
The Stanozolol hormone can be one of the few anabolic androgenic steroids women can use safely; while it is not the absolute mildest in nature for a woman it is up high on the list. Issues regarding the steroids hepatic nature as well as its effects on lipid profiles remain the same with women but the female athlete must also necessarily be aware of virilization. For the female athlete, the Winstrol side effects revolving around virilization will be the most concerning as such effects can destroy a womans femininity. Common virilization effects include a deepening of the vocal chords, body-hair growth and enlargement of the clitoris. The majority of women who supplement with the Stanozolol hormone, if they keep the dose low and use for very short periods will be fine. If you are a female Winstrol user and you begin to notice virilization symptoms simply discontinue use and you will be fine; nothing will change. It is when the symptoms are ignored, use is continued and the symptoms are allowed to set in that many women develop a problem; remember, man or woman responsible use is always your best friend.