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In 2010, unconfirmed reports speculated about the role mephedrone has played in the deaths of several young people in the UK. By July 2010, mephedrone had been alleged to be involved in 52 fatalities in the UK, but detected in only 38 of these cases. Of the nine that coroners had finished investigating, two were caused directly by mephedrone. [29] The first death reported to be caused by mephedrone use was that of 46-year-old, John Sterling Smith, [30] who had underlying health problems and repeatedly injected the drug. [31] A report in Forensic Science International in August 2010 stated mephedrone intoxication has been recorded as the cause of death in two cases in Scotland. Post mortem samples showed the concentration of mephedrone in their blood was 22 mg/L in one case and  mg/L in the other. [32] The death of a teenager in the UK in November 2009 was widely reported as being caused by mephedrone, but a report by the coroner concluded she had died from natural causes. [33] In March 2010, the deaths of two teenagers in Scunthorpe were widely reported by the media to be caused by mephedrone. Toxicology reports showed the teenagers had not taken any mephedrone and had died as a result of consuming alcohol and the heroin substitute methadone . [31] [34] According to Fiona Measham, a criminologist who is a member of the ACMD, the reporting of the unconfirmed deaths by newspapers followed "the usual cycle of ‘exaggeration, distortion, inaccuracy and sensationalism'" associated with the reporting of recreational drug use. [35]

12 th Pharmaceutical Sciences and Pharma Industry Conference February 26-27, 2018, London , UK; 7th European Biosimilars Conference , April 26-27, 2018, Rome, Italy ; 10 th Pharmacology Conferences during July 30-Aug 01, 2018 at Barcelona, Spain ; 4 th Marine Drugs and Natural Products Conferences , June 11-13, 2018 at Rome , Italy; 8 th Environmental Chemistry Conference , September 20-22, 2018 Berlin, Germany ; 9 th Pharmacovigilance Exhibition , June 21-22, 2018 at London, UK ; 4 th Antibiotics Conference ; June 14-15, 2018, Barcelona , Spain

“If we can operate in that gray area to help a bunch of kids who are out of options, so be it,” says Joel. The worst case scenario: their entire supply of Charlotte’s Web is seized, the thousands now receiving the medication are cut off and the Stanleys go to jail. “The first few years in this industry, I had nightmares every night of my kids watching me dragged out of the house in handcuffs,” says Joel. “But after we saw Charlotte and all these patients’ successes, it just became very real that you are living a life worth living and you are doing the right thing.”

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