Like other AAS, drostanolone is an agonist of the androgen receptor (AR).  It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity.  As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites .  While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives.  Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . 
The Oral Steroids Winstrol & Anavar:The Oral Steroids Winstrol & Anavar:The Oral Steroids Winstrol & Anavar:vWhile both of these oral steroids can be used for both bulking and cutting, most male anabolic steroid users will be better served using them as a part of a leaning or cutting cycle. Neither drug will produce abundant gains in size but they serve as a well refined tool in terms of holding on to strength as well as helping produce a harder physique. As it pertains to Winstrol, some may find a more suitable use during an off-season period in conjunction with other anabolic steroids; an increase in strength is always a welcomed attribute but do not expect to see the scale move upward in serious fashion due to Winstrol use. The same cannot be said of Anavar; most men will find Anavar suited only for cutting cycles but be aware, there are far better suited anabolic steroids we can use for this purpose but don’t be fooled, Anavar does have a place in both bulking and cutting cycles. Anavar is not only one of the best oral steroids for females it is one of the best anabolic steroids for female’s period. Due to its very mild effects Anavar is one of the safest anabolics a woman can use and in general at a very low dose and still see fantastic results. Anavar can be successfully used by women during both bulking and cutting cycles quite well.