16 years or older:
One drop in the affected eye(s) once a day in the evening
-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
-This drug should not be administered more than once a day since it has been shown that more frequent administration of prostaglandin analogs may decrease the intraocular pressure lowering effect.
-Reduction of the intraocular pressure starts approximately 4 hours after the first administration with maximum effect reached within approximately 8 to 12 hours.
Use: Reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension
Toxic glaucoma is open angle glaucoma with an unexplained significant rise of intraocular pressure following unknown pathogenesis. Intraocular pressure can sometimes reach 80 mmHg (11 kPa). It characteristically manifests as ciliary body inflammation and massive trabecular o edema that sometimes extends to Schlemm's canal . This condition is differentiated from malignant glaucoma by the presence of a deep and clear anterior chamber and a lack of aqueous misdirection. Also, the corneal appearance is not as hazy. A reduction in visual acuity can occur followed neuroretinal breakdown.