Epidural morphine and steroid paste complications

Initially, inject 5 mg epidurally in the lumbar region and assess the patient in 1 hour; if pain relief is not adequate at that time, administer incremental doses of 1 to 2 mg, with sufficient time between injections to appropriately assess for efficacy. The manufacturer recommends a maximum of 10 mg per 24 hours. For continuous epidural infusion, initiate at 2 to 4 mg per 24 hours, with additional doses of 1 to 2 mg given if pain relief is not initially achieved. The incidence of early and late respiratory depression is dramatically increased with thoracic administration. Use preservative-free formulations only.

Hi! I had epidural with both of my children, the second one was a nightmare! While performing the epidural the anesthesiologist punctured a layer called the duramadre, so he just told me i would have headache. I was sent home the next day, with a horrible migrain, they told me it was normal. The pain continued for several days, it was as if someone whas whipping my brain. This continued for a week, finally i was desoriented, confused and couldnt feel my face, my husband tono me to the hospital where i had an mri and venography, the results where horrifying. Cerebral venous thrombosis, 5 of them! Plus 2 cerebral hematomas. Hospitalized for 10 days, blood thinners for a year, lots of medication, no breastfeeding for my child! All this caused by the epidural and the puncture of the duramadre with no proper management! Horrible experience!

This is awful,and you need to understand that it’s not you. My belief from what you described is there is real damage to you cord, muscles, and nerves at the location. I personally went in for a C4-5 bone graft, and was woke with a C4,5,6,7 cage installation, 2 different neck cuts to access the site, and in pain as if the surgery was still being 4th day of refusing to leave,unable too. On 5th day I was able to stand and walk loaded with alot of IV pain discharged me that evening, 9 days later I barely made it in for visit,4 weeks later i found myself being dismissed when unable to walk, speak, lose control of my urine. In short it was the beginning of nothing else I can do, to i won’t see you again, and had me removed using the police. This was back in Dec3,2013, now I’ve got narrowing of the spinal cord at every level of the c2,3,4,7, now same at the L1,2,3,4,and S1. Since this I’ve been provoked to no pain meds, always u need pain pump,i injections, and suffering until insane. If I had the chance to go back in time, I’d went to assisted living where they had to manage the pain, and rest until I got better. In short I went to Florida, done nothing but rest for 7 months before I got to this point of variable pain. They are slow killing is, and don’t care what you go through as they dont even remember you doctor visits. It was hard to except. My point is, Everytime I listen to them instead of my body, I was just a pitiful mess. You need to get with the best spine people and pray they can fix it, but don’t worry about getting back to normal or even the simplistic things as it will take you back to hell and it takes longer Everytime you have flare it up. I laid like a vegetable for 18 months before I figured it out. Now I’m in bad shape and they are offering only injections, I’m thinking really hard, shame they are not made to get you better. This is what’s going on with society today, they’ll have to answer one day. But you make sure your not stubborn like I was and demand treatment it takes and the proper care. I’m praying for you, and I hope we get this country on the right track again as well as the compassion for others comes back

Additionally, delayed sexual maturation and decreased sexual behaviors in female offspring at 20 mg/kg/day ( times the HDD), and decreased plasma and testicular levels of luteinizing hormone and testosterone, decreased testes weights, seminiferous tubule shrinkage, germinal cell aplasia, and decreased spermatogenesis in male offspring were also observed at 20 mg/kg/day ( times the HDD). Decreased litter size and viability were observed in the offspring of male rats that were intraperitoneally administered morphine sulfate for 1 day prior to mating at 25 mg/kg/day ( times the HDD) and mated to untreated females. Decreased viability and body weight and/or movement deficits in both first and second generation offspring were reported when male mice were treated for 5 days with escalating doses of 120 to 240 mg/kg/day morphine sulfate ( to times the HDD) or when female mice treated with escalating doses of 60 to 240 mg/kg/day ( to times the HDD) followed by a 5-day treatment-free recovery period prior to mating. Similar multigenerational findings were also seen in female rats pre-gestationally treated with escalating doses of 10 to 22 mg/kg/day morphine ( to times the HDD).

A couple thoughts, and let me start by saying I am fairly new to spine issues. I have an L5-S1 large bulging disc pressing on the right Sciatic Nerve. Significant pain for one month. Probably not the person to give advice (some posters have earned a PhD in pain not by choice) but reading your post made me want to offer what I have found. I hope you find an answer, you deserve it. 1. Medical advice needs to come from multiple sources so if you have yet to seek alternative opinions probably best to do that now. 2. I personally believe the cycle of pain requires an element of finding your means to break it. I found the best, all be it hard thing to do was to push myself out for a walk and also to go to work. I believe there is a tough balance with this that requires hearing the medical advice to know when to not push it but also knowing if you don't push a bit then the pain owns us. 3. At 7 months, I can't help but think the conservative approach isn't working and you should be talking to a surgeon. Again, I hope you find an answer.

Breastfed newborns of mothers using intravenous PCA morphine for postcesarean analgesia were more alert and better oriented after postpartum day 3 than infants of mothers using intravenous PCA meperidine and nonbreastfed control infants. There was no difference in newborn respiratory rates. The authors stated that the mothers of nonbreastfed infants had greater parity than the breastfeeding mothers which, combined with a presumed lower desire to breastfeed, may have contributed to the lower behavioral and alertness scores in the nonbreastfed newborns.[7][14]

Epidural morphine and steroid paste complications

epidural morphine and steroid paste complications

Additionally, delayed sexual maturation and decreased sexual behaviors in female offspring at 20 mg/kg/day ( times the HDD), and decreased plasma and testicular levels of luteinizing hormone and testosterone, decreased testes weights, seminiferous tubule shrinkage, germinal cell aplasia, and decreased spermatogenesis in male offspring were also observed at 20 mg/kg/day ( times the HDD). Decreased litter size and viability were observed in the offspring of male rats that were intraperitoneally administered morphine sulfate for 1 day prior to mating at 25 mg/kg/day ( times the HDD) and mated to untreated females. Decreased viability and body weight and/or movement deficits in both first and second generation offspring were reported when male mice were treated for 5 days with escalating doses of 120 to 240 mg/kg/day morphine sulfate ( to times the HDD) or when female mice treated with escalating doses of 60 to 240 mg/kg/day ( to times the HDD) followed by a 5-day treatment-free recovery period prior to mating. Similar multigenerational findings were also seen in female rats pre-gestationally treated with escalating doses of 10 to 22 mg/kg/day morphine ( to times the HDD).

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