Clenbuterol can induce fat burning via beta-2-adrenergic agonism; it is a highly selective B2 agonist. Via this mechanism, it induces fat burning by increases intra-cellular levels of cyclic AMP which has downstream effects on inducing protein kinase A (PKA) activity  which then acts on hormone sensitive lipase (HSL) and perilipin to mediate lipolysis;  insulin is a negative mediator of this pathway.  PKA may also induce CREB phosphorylation, which is then able to induce JHDM2a (a histone demethylase) promoter activity  and may have downstream influences on PPARα and UCP1, two proteins involved in fatty acid oxidation and uncoupling (respectively).
“It’s a huge injustice,” Contador said. “It’s something that’s going to stay with me my whole life.” More Alberto Contador news
Contador won his second Tour de France on 26 July 2009 with a winning margin of 4'11" over Andy Schleck . He finished 5'24" ahead of Lance Armstrong , who finished third in his return to the Tour after a four-year absence.  Contador had won the last four Grand Tour races that he had entered. During the celebration at the podium, the organizers of the Tour wrongly played the Danish National Anthem instead of the Spanish Royal March .   In the aftermath of the tour, Contador and Armstrong engaged in a war of words, with Contador quoted as saying that, although Armstrong "is a great rider and [..] did a great Tour[, but] on a personal level [..] I have never admired him and never will", and Armstrong responding that "a champion is also measured on how much he respects his teammates and opponents."  The sniping caused others, such as the director of the Tour, to wonder "what it would have been like to have had Contador and Armstrong in different teams."  Contador later described the experience as "psychologically tough", likening it to having to compete in two races – one on the road, the other in the team hotel. Armstrong's control of the team during the race extended to its entire fleet of team cars, forcing Contador to rely on his brother to take him from stage finishes to the hotel.